Relationship between interstitia and prognosis of gastric carcinoma.

Excluding cases of early carcinoma, curative surgery for gastric carcinoma was performed in 149 patients from 1969 to 1978. Among them 77 had adenocarcinoma with a large amount of interstitial connective tissue (scirrhous type), and 72 had adenocarcinoma with a comparatively small amount of connective tissue (non-scirrhous type). The overall survival rate was low among those with scirrhous type (NO.095). However, in comparing 14 cases (18.1%) of pT2 carcinoma of scirrhous type with 22 cases (32.7%) of pT2 carcinoma of non-scirrhous type, the survival ratio of those of scirrhous type exceeded that of those of non-scirrhous type (P*O.045). The proliferation of interstitia in metastatic lesions of the lymph nodes was not always the same as that in the primary lesion. The prognosis of carcinoma in cases of lymphatic metastasis with a large amount of connective tissue (scirrhous type) was better than that in those with a small amount of connective tissue (non-scirrhous type).